Recent advances in the field of tissue engineering and regenerative medicine not only open new avenues to replace and regenerate tissues and organs but also have the potential to correct some birth defects via lab-grown organs and tissue, bioartificial organs, or using xenogeneic organs. Furthermore, the cost of organ transplantation and medication followed by surgery cannot be afforded by people belonging to low socioeconomic groups or middle-income countries. Besides this, there are very few hospitals that have equipment for organ preservation and transplantation which further limits the usage of organs of brain-dead patients. Another challenge is to convince family members for organ donation of their loved ones who are on life support due to deceased or brain-dead situations. Apart from the ethical approval–related hurdles and lack of awareness, organ donation comes with a bag of challenges which include red-tapism and king-sized paperwork. The organ transplantation process seems too easy but identifying a perfect match of the organ is very difficult. Organs such as the kidney, liver, pancreas, lungs and heart, eyes, skin, bone, bone marrow, nerves, brain, heart valves, eardrum, ear bones, and blood can be donated. A deceased donor or a living donor can donate 25 different organs or tissues which can save as many lives as possible. In this world, half of a million patients are estimated on the waiting list for an organ transplant, and due to the inaccessibility of organs, mortality rates increase due to the failure of a vital organ. Furthermore, information about commercially available 3D printers has also been included in this article. This review dealt with the current approaches for tissue and organ engineering including methods of scaffold designing, recent advances in 3D bioprinting, organs regenerated successfully using 3D printing, and extended application of 3D bioprinting technique in the field of medicine. Besides this, the decellularization of organs and using this as a scaffold for generating new organs through the recellularization process shows promising results. In this context, major advances and innovations are being made in the fields of tissue engineering and regenerative medicine which have a huge impact on the scientific community is three-dimensional bioprinting (3D bioprinting) of tissues and organs. Recent, advances in the field of biogenerative engineering have the potential to regenerate tissues and create organs compatible with the patient’s body. Today’s need for organs for the transplantation process in order to save a patient’s life or to enhance the survival rate of diseased one is the prime concern among the scientific community. Besides this, information about commercially available 3D printers has also been included in this article. This review discussed about current approaches for tissue and organ engineering including methods of scaffold designing, recent advances in 3D bioprinting, organs regenerated successfully using 3D printing, and extended application of 3D bioprinting technique in the field of medicine. ![]() Recently, technological advancements in the field of biogenerative engineering have the potential to regenerate tissues and, in some cases, create new tissues and organs. ![]() This led to day-day-increase in the number of patients on transplant waiting lists as well as in the number of patients dying while on the queue. The unavailability of adequate organs for transplantation to meet the existing demand is a major challenge in the medical field. Organ or cell transplantation is medically evaluated for end-stage failure saving or extending the lives of thousands of patients who are suffering from organ failure disorders.
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